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- Mar 2008
- 18786
- Revelling In The Hole
- England, Chelsea and Tooting and Mitcham. And Surrey CCC. And Wimbledon Dons Speedway (RIP)
- Nairn's Cheese Oatcake
Originally posted by San Bernardhinault View PostThe horrible thing about that is that all these fascist politicans who got together at Mar a Lago will get great treatment and therefore take treatment away from people who aren't fascist cunts. None of them are going to die a horrible death, they'll just suck up resources from decent people.
I mean, are we absolutely certain that gravy browning or whatever it is that Trump smears all over his face isn't actually an effective barrier to COVID-19 transmission?
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Our household has been sheltering in place since Thursday, so uh, we're ahead of the curve I guess. We're down to just the one gallon of milk with children who consume a ridiculous amount of it though, we're discussing whether to add an additional CSA box order to get more on Friday or whether one of us will go on a mission this week to restock.
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Originally posted by Rogin the Armchair fan View PostThe thing of New Zealand and Australia "ordering" people to self-isolate on arrival. How are they planning to enforce that? Surely by its nature it's "politely asking" at best, and something that very few travellers are going to comply with?
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Originally posted by anton pulisov View PostI can't think properly.
Can anybody give me some good news / positive scenarios?
People adhere to short-term lock down for three weeks or so, the virus does not spread and those who have it recover and have the antibodies. With transmission stopped, the virus basically just dies out in its few carriers, and the whole thing is done and dusted in a handful of weeks.
(Relatively) Good news is that almost all the disruption we've had has come from people acting responsibly to contain and prevent the spread. This means that society is acting as a society and is willing to accept a degree of pain for the greater good. And that as people (and organisations, and certain governments) are behaving responsibly with an eye of communal wellbeing, there is a chance of making the impacts of the disease (comparatively) less-bad.
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Oh fuck, did you read this?
I treat patients who are proven to have coronavirus. One week ago, I was wearing full PPE [personal protective equipment]. That consists of a proper FFP3 mask [offering high respiratory protection], a visor, a surgical gown, and two pairs of gloves.
Now we’ve been told not to bother with any of that. They’ve told us “just treat it as though it’s seasonal flu”. Now we are expected to wear just a normal surgical mask, a pair of ordinary short gloves, and a plastic apron that doesn’t cover all of you like a surgical gown does.
Meanwhile, it emerged that GP practices in about 20 parts of England have been supplied with face masks that expired in 2016 but purported to be useable until next year. Pulse, a website for GPs, disclosed that stickers on batches of masks saying “best before 2016” had been covered over with new stickers reading “2021”.Last edited by DCI Harry Batt; 16-03-2020, 23:17.
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Originally posted by San Bernardhinault View Post
Best case scenario
People adhere to short-term lock down for three weeks or so, the virus does not spread and those who have it recover and have the antibodies. With transmission stopped, the virus basically just dies out in its few carriers, and the whole thing is done and dusted in a handful of weeks.
(Relatively) Good news is that almost all the disruption we've had has come from people acting responsibly to contain and prevent the spread. This means that society is acting as a society and is willing to accept a degree of pain for the greater good. And that as people (and organisations, and certain governments) are behaving responsibly with an eye of communal wellbeing, there is a chance of making the impacts of the disease (comparatively) less-bad.
Here in Sweden the schools are still open and people aregoing to work.
The Dutch seem to be going for some kind of semi lockdown and slow infection of the entire population.
I agree with you that everyone should just stay home for many weeks*. Cut off all infection routes and let it die out in the immune systems of the various people who have it. Next year we will have vaccine.
Have to hand it to catholic Europe, they put the people ahead of the economy.
*But will the Netflix servers be able to cope
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Report from the retail frontline:
Fucking hell. People are morons. They are also rude, selfish, ignorant and several other adjectives.
People are addicted to consumerism, and any possibility of it being taken away leads them to have a breakdown. They carry on shopping for stuff they don't and won't need, and are aggressive and confrontational when denied the chance to hoard some more.
They are shopping in large groups, spending time browsing the non-essentials like clothing and houseware. These people are completely incapable of following guidance or showing any sort of self-restraint.
Meanwhile, on the buses and out in town I would estimate 50% of passengers do not need to be there, especially on the homeward journey, which picks up outside a pub, and the usual crowd of elderly pissheads were volubly debating the government advice that they should modify their behaviour.
We need to adopt the Italian authoritarian approach as soon as we can. No measures are too draconian in my opinion. Everybody out on the streets needs to be challenged and sent back home/arrested if they can't come up with a reason why they are out. Because the general public are fucking idiots who can't follow any sort of instruction as it doesn't apply to them.
Other than that I had a great first day back at work.
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Majority of Florida infections were caught while traveling, according to this:
[URL]https://twitter.com/PatriciaMazzei/status/1239700236530069504/photo/1[/URL]
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- Mar 2008
- 18786
- Revelling In The Hole
- England, Chelsea and Tooting and Mitcham. And Surrey CCC. And Wimbledon Dons Speedway (RIP)
- Nairn's Cheese Oatcake
Originally posted by San Bernardhinault View Post
Best case scenario
People adhere to short-term lock down for three weeks or so, the virus does not spread and those who have it recover and have the antibodies. With transmission stopped, the virus basically just dies out in its few carriers, and the whole thing is done and dusted in a handful of weeks.
(Relatively) Good news is that almost all the disruption we've had has come from people acting responsibly to contain and prevent the spread. This means that society is acting as a society and is willing to accept a degree of pain for the greater good. And that as people (and organisations, and certain governments) are behaving responsibly with an eye of communal wellbeing, there is a chance of making the impacts of the disease (comparatively) less-bad.
I really hope that you're on the right track here but I haven't heard anyone suggest that the virus can be terminated in such a way. The only way that you stop a virus or disease propagating is building up the herd immunity. The heavily restrictive social measures should reduce the spread and give the health authorities time to build up their ventilator numbers and supply of PPE but when the restrictions are eased, as they eventually will have to be, numbers will rise again. It's a highly transmissable virus. To travel around the world at the speed it has is almost unprecedented.
As for a vaccine, in a year perhaps. Maybe a year-and-a-half or even two.
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Originally posted by Nocturnal Submission View Post
I really hope that you're on the right track here but I haven't heard anyone suggest that the virus can be terminated in such a way. The only way that you stop a virus or disease propagating is building up the herd immunity. The heavily restrictive social measures should reduce the spread and give the health authorities time to build up their ventilator numbers and supply of PPE but when the restrictions are eased, as they eventually will have to be, numbers will rise again. It's a highly transmissable virus. To travel around the world at the speed it has is almost unprecedented.
As for a vaccine, in a year perhaps. Maybe a year-and-a-half or even two.
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I'm not convinced that a vaccine is likely given that attempts at creating various cold vaccines, MERS and SARS vaccines have not been successful. But they are testing them and accelerating the process.
NS: I don't think anyone expects that the virus would be wiped out the way I suggested. I'm just saying that it's a best-possible-case scenario. It should theoretically work. The fact that the curves have flattened out in Korea and China suggests that there's something to it. The Koreans are nowhere near herd immunity, and yet their infection rate has collapsed.
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- Mar 2008
- 18786
- Revelling In The Hole
- England, Chelsea and Tooting and Mitcham. And Surrey CCC. And Wimbledon Dons Speedway (RIP)
- Nairn's Cheese Oatcake
Originally posted by anton pulisov View Post
Vaccine. What about antiviral treatment? Some lads in Belgium managed to cultivate antibodies
Way above my pay grade, but Wiki is quite informative:
Antiviral
No medication has yet been approved to treat coronavirus infections in humans by the WHO although some are recommended by the Korean and Chinese medical authorities.[139] Trials of many antivirals have been started in COVID-19 including oseltamivir, lopinavir/ritonavir, ganciclovir, favipiravir, baloxavir marboxil, umifenovir, and interferon alfa but currently there are no data to support their use.[140] Korean Health Authorities recommend lopinavir/ritonavir or chloroquine[141] and the Chinese 7th edition guidelines include interferon, lopinavir/ritonavir, ribavirin, chloroquine and/or umifenovir.[142]
Research into potential treatments for the disease was initiated in January 2020, and several antiviral drugs are already in clinical trials.[143][144] Although completely new drugs may take until 2021 to develop,[145] several of the drugs being tested are already approved for other antiviral indications, or are already in advanced testing.[139]
Remdesivir and chloroquine effectively inhibit the coronavirus in vitro.[93] Remdesivir is being trialled in US and in China.[140]
Preliminary results from a multicentric trial, announced in a press conference and described by Gao, Tian and Yang, suggested that chloroquine is effective and safe in treating COVID-19 associated pneumonia, "improving lung imaging findings, promoting a virus-negative conversion, and shortening the disease course".[94]
Recent studies have demonstrated that initial spike protein priming by transmembrane protease serine 2 (TMPRSS2) is essential for entry of SARS-CoV-2, SARS-CoV and MERS-CoV via interaction with the ACE2 receptor.[146][147] These findings suggest that the TMPRSS2 inhibitor Camostat approved for clinical use in Japan for inhibiting fibrosis in liver and kidney disease, postoperative reflux esophagitis and pancreatitis might constitute an effective off-label treatment option.[146]
Passive antibody therapy
Using blood donations from healthy people who have already recovered from COVID-19 holds promise,[148] a strategy which has also been tried for SARS, an earlier cousin of COVID-19.[148] The mechanism of action is that the antibodies naturally produced in the immune systems of those who have already recovered are transferred to people in need of them via a nonvaccine form of immunization.[148] Such convalescent serum therapy (antiserum therapy) is also analogous to the way that hepatitis B immune globulin (HBIG) is used to prevent hepatitis B or human rabies immune globulin (HRIG) is used to treat rabies.[148] Other forms of passive antibody therapy, such as with manufactured monoclonal antibodies, may come later after biopharmaceutical development,[148] but convalescent serum production could be increased for quicker deployment.[149]
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- Mar 2008
- 18786
- Revelling In The Hole
- England, Chelsea and Tooting and Mitcham. And Surrey CCC. And Wimbledon Dons Speedway (RIP)
- Nairn's Cheese Oatcake
Originally posted by San Bernardhinault View PostI'm not convinced that a vaccine is likely given that attempts at creating various cold vaccines, MERS and SARS vaccines have not been successful. But they are testing them and accelerating the process.
NS: I don't think anyone expects that the virus would be wiped out the way I suggested. I'm just saying that it's a best-possible-case scenario. It should theoretically work. The fact that the curves have flattened out in Korea and China suggests that there's something to it. The Koreans are nowhere near herd immunity, and yet their infection rate has collapsed.
Yes, but it's such early days in the outbreak, SB. If there is no re-emergence of the virus when both countries loosen restrictions I'll be encouraged, but that's yet to be tested.
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Originally posted by San Bernardhinault View PostI'm not convinced that a vaccine is likely given that attempts at creating various cold vaccines, MERS and SARS vaccines have not been successful. But they are testing them and accelerating the process.
NS: I don't think anyone expects that the virus would be wiped out the way I suggested. I'm just saying that it's a best-possible-case scenario. It should theoretically work. The fact that the curves have flattened out in Korea and China suggests that there's something to it. The Koreans are nowhere near herd immunity, and yet their infection rate has collapsed.
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- Mar 2008
- 18786
- Revelling In The Hole
- England, Chelsea and Tooting and Mitcham. And Surrey CCC. And Wimbledon Dons Speedway (RIP)
- Nairn's Cheese Oatcake
Originally posted by EIM View PostMy best mate was told to lose 80% of his staff today. His bar is now five days a week, staffed by management only. This is heartbreaking.
I feel for you and him.
Sunak is going to announce additional business support measures tomorrow. Macron has pledged EUR300bn support for French businesses and said that none need go bankrupt. Let's see how we measure up.
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